Fig. 8: Proposed role of PT in the development of fruit with pointed tips in tomato.
From: Variation in the fruit development gene POINTED TIP regulates protuberance of tomato fruit tip
In this model, an SNP (A/G) in PT leads to the translation of either of two protein products, PTH and PTR. PTH contains three C2H2 domains. PTR has only two C2H2 domains. A knockout mutation in PTH leads to the development of fruit with pointed tips. PTH is a transcription repressor that downregulates the expression of FUL2 by binding the FUL2 promoter with a higher affinity than PTR, alters the auxin transport, and inhibits the formation of fruit with pointed tips in tomato.
