Fig. 4: Causal effects of risk factors on stroke outcomes.
MR analyses of the effect of risk factors on stroke outcomes. The squares are the causal estimates on the OR scale, and the whiskers represent the 95% confidence intervals for these ORs. N_SNPs number of SNPs used for the estimation of the causal effects in this plot. P values were determined from the inverse-variance-weighted two-sample MR method. Statistical heterogeneity was assessed using the I2 statistic. OR odds ratio, SBP systolic blood pressure, AF atrial fibrillation, WMH white matter hyperintensity, T2D type 2 diabetes, BMI body mass index, Smoking smoking initiation.
