Table 2 Effect of remdesivir plus standard of care (SoC) compared to SoC only on patient-relevant outcomes after 1 year from hospitalization due to COVID-19-infection

From: Effect of remdesivir post hospitalization for COVID-19 infection from the randomized SOLIDARITY Finland trial

Outcome (Option categories in questionnaire)

Remdesivir, n = 98 (%)

SoC, n = 83 (%)

RR, 95% CI

How do you feel you have recovered from the COVID-19 infection you had a year ago?

  

0.94, 0.47–1.90

Fully or largely (1–2)

83 (84.7)

71 (85.5)

 

About halfway recovered to not recovered at all (3–5)

15 (15.3)

12 (14.5)

 

Exertional dyspnea, mMRC dyspnea scale

  

0.61, 0.20–1.85

No to slight dyspnea (mMRC 0–1)

92 (93.9)

76 (91.6)

 

At least a need to walk slower than usually (mMRC 2–4)

5 (5.1)

7 (8.4)

 

Excluded (paralyzed before COVID-19)

1

0

 

Fatigue

  

0.88, 0.54–1.44

No or slight fatigue (1–2)

74 (75.5)

60 (72.2)

 

Moderate or severe fatigue (3–4)

24 (24.5)

23 (27.7)

 

Mobility, walking (EQ-5D-5L)

  

1.03, 0.54–1.96

No or slight problems (1–2)

81 (82.7)

69 (83.1)

 

From moderate problems to unable to walk (3–5)

17 (17.3)

14 (16.9)

 

Self-care, washing or dressing oneself (EQ-5D-5L)

  

0.51, 0.13–2.08

No or slight problems (1–2)

95 (96.9)

78 (94.0)

 

From moderate problems to inability to wash or dress (3–5)

3 (3.1)

5 (6.0)

 

Usual activities, e.g., work, study, housework, family or leisure activities (EQ-5D-5L)

  

0.71, 0.32–1.55

No or slight problems (1–2)

88 (89.8)

71 (85.5)

 

From moderate problems to inability to do usual activities (3–5)

10 (10.2)

12 (14.5)

 

Pain or discomfort (EQ-5D-5L)

  

0.85, 0.44–1.63

No or slight pain (1–2)

83 (84.7)

68 (81.9)

 

From moderate to extreme pain (3–5)

15 (15.3)

15 (18.1)

 

Anxiety or depression (EQ-5D-5L)

  

1.27, 0.47–3.42

No or slight problems (1–2)

89 (90.8)

77 (92.8)

 

From moderate to extreme problems (3–5)

9 (9.2)

6 (7.2)