Fig. 2: Deletion of DNMT3A results in complex mRNA expression changes in Caco-2 cells. | Nature Communications

Fig. 2: Deletion of DNMT3A results in complex mRNA expression changes in Caco-2 cells.

From: DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon

Fig. 2

a Schematic representation of cell lines generation and data analysis workflow. Graphical elements modified from ref. 17. b Heatmaps of differentially expressed genes (DEGs) of WT, ΔDNMT3A, DNMT3A1, and DNMT3A2 cell lines (n = 4). Scaled gene expression/methylation intensity across all samples are plotted.

Back to article page