Fig. 8: Expression of HSF1 might serve as a marker to monitor AML status.
From: HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia
a HSF1 H-score index in AML samples at diagnosis, remission, or relapse (n = 39 primary AML samples). Box plots show median and first/third quartiles. ANOVA with LSD post-hoc analysis was used, *p = 0.0001. b–f Representative pictures showing 2 different HSF1 staining patterns in AML patients. b–c Pattern 1, HSF1 staining at remission (b) and follow up (c). d–f Pattern 2, HSF1 staining at remission (d), follow up (e) and relapse (f). Note that (b) and (d) are 2 weeks post chemotherapy, BM shows 5–10% of cellularity. The insets in (b) and (d), are HSF1 staining at AML diagnosis. Scale bar, 20 μM. Source data are provided as a Source Data file.
