Fig. 7: The LacAC4A promoting the diabetic ulcer wound healing. | Nature Communications

Fig. 7: The LacAC4A promoting the diabetic ulcer wound healing.

From: Lactose azocalixarene drug delivery system for the treatment of multidrug-resistant pseudomonas aeruginosa infected diabetic ulcer

Fig. 7

a The mechanism schematic of Cip@LacAC4A to promote diabetic wound healing in vivo. b H&E and Masson staining of wound regeneration after various treatments on day 7. c The thickness of granulation tissue after various treatments on day 7. d The expression of VEGF factor after various treatments on day 7. e Immunohistochemistry of TNF-α and IL-6 stained and immunofluorescence of ROS and CD31-stained images. Scale bar was 100 nm. f Quantitative analysis of TNF-α of wound tissues on day 7. g Quantitative analysis of ROS of wound tissues on day 7. h Quantitative analysis of CD31 of wound tissues on day 7. Data are presented as mean ± SD, n = 3, *p < 0.05, **p < 0.01, ***p < 0.001.

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