Fig. 5: BAMs do not engulf microglial debris in vivo. | Nature Communications

Fig. 5: BAMs do not engulf microglial debris in vivo.

From: Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice

Fig. 5

a Scheme of tamoxifen-triggered microglial cell death for investigating the BAM engulfment capacity of microglial debris. b Meningeal, choroid plexus or perivascular macrophages do not engulf parenchymal microglia upon microglial ablation. N = 6 mice in each group. Two-tailed independent t test. MΦ meningeal macrophage, CPΦ choroid plexus macrophage, PVΦ perivascular macrophage. Data are presented as mean ± SD. The source data are provided as a Source Data file.

Back to article page