Table 5 Odds ratios for the association between SARS-CoV-2 infection and ectopic pregnancy from multinomial logistic regression models

From: A population-based matched cohort study of early pregnancy outcomes following COVID-19 vaccination and SARS-CoV-2 infection

 

Number of pregnancies

Number (%) of ongoing pregnancies

Number (%) of ectopic pregnancies

Odds ratio (95% CI)a

p-value

Adjusted Odds ratio (95% CI)b

p-value

Primary analysis (historical controls)

Uninfected

2745

1960 (71.4%)

33 (1.2%)

1

 

1

 

Infected

915

579 (63.3%)

8 (0.9%)

0.80 (0.37–1.75)

0.58

0.76 (0.34–1.69)

0.50

Supplementary analysis (contemporary controls)

Uninfected

2745

1901 (69.3%)

32 (1.2%)

1

 

1

 

Infected

915

579 (63.3%)

8 (0.9%)

0.82 (0.37–1.78)

0.61

0.78 (0.34–1.79)

0.56

  1. All analyses exclude women who received COVID-19 vaccination between 6 weeks preconception and the earliest of either: end of pregnancy or the end of the exposure period at 2 + 6 weeks gestation.
  2. CI confidence interval.
  3. aAdjusting for matching factors: maternal age and gestational age at the date of infection of index infected pregnancy (and season of conception for primary analysis).
  4. bAdditionally adjusting for deprivation, urban/rural status, and clinical vulnerability (and ethnicity and season of conception in supplementary analysis).
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