Fig. 1: AXL expression in human normal and NSCLC tissues and lung cancer cell lines.

a Detection of AXL expression in NSCLC samples by IHC. Representative images (magnification × 400) are shown (n = 90). Scale bar represents 100 μm. b, c Detection and quantification of AXL expression by western blotting in eight pairs of EGFR-TKI resistant NSCLC tissues (T) and adjacent normal lung tissues (N). Each group n = 8. One of three repetitions with similar results is shown and presented as the mean ± SD (T vs N p < 0.0001, two-sided unpaired t-test). d, e Detection of AXL expression by western blotting and flow cytometry in human NSCLC cell lines A549, HCC827-ER3, and HCC827. One of three repetitions with similar results is shown here. *p < 0.05, **p < 0.01, ***p < 0.001. Source data are provided as a Source Data file.