Fig. 7: An integrated elastic net model of clinical and genomic features predicts response to ICI.

a The predictor coefficients are shown for the final model trained on the entire discovery set. b The receiver operating characteristic curves are shown for the model performance on the validation portion of the IMvigor210 dataset (n = 51), and the entire UNC-108 (n = 88), and UC-GENOME (n = 166) independent datasets. Source data are provided as a Source Data file.