Table 1 Predicted gene expression in blood-COVID-19 associations for likely causal genes based on COVID-19 Host Genetics Initiative data
Chromosome | Gene | R2 | COVID-B2 | COVID-A2 | ||
|---|---|---|---|---|---|---|
Direction | p | Direction | p | |||
3 | ACTL6A | 0.008 | − | 9.9 × 10−19 | − | 2.5 × 10−1 |
3 | LRRC2 | 0.044 | − | 5.4 × 10−9 | − | 3.9 × 10−5 |
3 | RP11-24F11.2 | 0.006 | − | 8.8 × 10−12 | − | 9.0 × 10−6 |
3 | FLT1P1 | 0.116 | − | 3.3 × 10−14 | − | 1.0 × 10−7 |
3 | CCR5 | 0.049 | − | 9.9 × 10−19 | − | 1.8 × 10−6 |
12 | OAS1 | 0.056 | − | 1.4 × 10−7 | − | 1.2 × 10−8 |
12 | OAS3 | 0.041 | + | 2.7 × 10−8 | + | 3.4 × 10−11 |
17 | LRRC37A4P | 0.668 | + | 2.6 × 10−6 | + | 3.5 × 10−3 |
17 | RP11-707O23.5 | 0.599 | − | 2.8 × 10−6 | − | 3.4 × 10−3 |
17 | DND1P1 | 0.489 | − | 2.7 × 10−6 | − | 3.3 × 10−3 |
21 | IFNAR2 | 0.037 | − | 2.2 × 10−11 | − | 2.2 × 10−9 |
