Fig. 3: Intestinal contents SCFA (short-chain fatty acids) increased while serum LBP decreased with post-FMT stool colonization compared to pre-FMT. | Nature Communications

Fig. 3: Intestinal contents SCFA (short-chain fatty acids) increased while serum LBP decreased with post-FMT stool colonization compared to pre-FMT.

From: Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice

Fig. 3

A Butyrate after colonization with entire stool, B Butyrate in germ-free mice and those colonized using sterile supernatants from pre and post-FMT mice. C Isocaproate after colonization with entire stool, D Isocaproate in germ-free mice and those colonized using sterile supernatants from pre and post-FMT mice. Data presented as mean and 95% CI (boxplot) with individual values and the entire range in the error bars. E Serum lipopolysaccharide binding protein (LBP) reduced after colonization with entire stool in post-FMT vs pre-FMT (p = 0.0074 Mann–Whitney test), F Serum LBP in germ-free mice and those colonized using sterile supernatants from pre and post-FMT mice (p = 0.88 Kruskal–Wallis test). Data presented as median and 95% CI (boxplot) and individual values and the entire range in the error bars. Pre Pre-FMT entire stool, Post Post-FMT entire stool, GF germ-free, PreSup GF supernatant Pre-FMT, PostSup GF supernatant Post-FMT, D1 day 1, D2 day 2. ***p < 0.001,*p < 0.05, NS not significant. 14 mice per group for entire stool. 6 per group in GF, PreSup and 4 in PostSup experiments.

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