Fig. 2: Reversion mutations in germline BRCA1/2 carriers.

A The nucleotide and protein coding sequence for the germline and somatic reversion mutations are shown with respect to the reference genome for patients with BRCA1 (n = 3) and BRCA2 (n = 8) somatic reversion mutations. B Oncoprint showing clinical characteristics and somatic alterations for all patients with BRCA1/2 reversion mutations.