Fig. 3: Carriers of both germline pathogenic/likely pathogenic (P/LP) variant in a CDC Tier 1 condition and pharmacogenetic variant associated with an actionable phenotype to drugs used for treatment. | Nature Communications

Fig. 3: Carriers of both germline pathogenic/likely pathogenic (P/LP) variant in a CDC Tier 1 condition and pharmacogenetic variant associated with an actionable phenotype to drugs used for treatment.

From: Analysis of clinically relevant variants from ancestrally diverse Asian genomes

Fig. 3

Only pharmacogenetic variant-drug combinations supported by PharmGKB Level 1A/1B evidence were considered. HBOC hereditary breast and ovarian cancer syndrome, LS Lynch syndrome, FH familial hypercholesterolemia, n number of germline P/LP variant carriers for the indicated CDC Tier 1 genetic conditions among 9051 Singaporeans.

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