Fig. 2: Evaluation of T HIV-specific T cell responses to four HIV-1 antigens. | Nature Communications

Fig. 2: Evaluation of T HIV-specific T cell responses to four HIV-1 antigens.

From: Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8+ T cell immunity

Fig. 2

Net frequency of HIV-specific CD8+ AIM+ T cells for each independent stimulation (Env, Gag, Nef and Pol) plotted by box plot for a, ART-control and individuals receiving 3BNC117 (+/− RMD). b ART-control and 3BNC117 sensitive individuals receiving 3BNC117 (+/− RMD). c ART-control and resistant 3BNC117 individuals receiving 3BNC117 (+/− RMD). Longitudinally collected PBMCs were available and analyzed for 40 individuals from which at least one timepoint was included (n = 14 ART-control group, n = 15 3BNC117 sensitive and n = 11 3BNC117 resistant individuals receiving the bNAb (+/− RMD)). Box-and-whisker plots show median values (center line), 25th to 75th percentiles (box outline), and the range of values (whiskers). P-values were calculated using two-sided paired Wilcoxon test when comparing longitudinal data of the same group and by two-sided Mann–Whitney test when comparing two different groups. Source data are provided as a Source Data file.

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