Fig. 3: Substrate scope of copper-catalyzed S-amidation of thiols with dioxazolones. | Nature Communications

Fig. 3: Substrate scope of copper-catalyzed S-amidation of thiols with dioxazolones.

From: Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols

Fig. 3

Isolated yield by silica gel column chromatography at 0.1–0.4 mmol scale. aThiocarbamate side product 33’ was obtained in 49% yield. bCondition [C]: S (2 equiv), D (1 equiv), CuOAc (10 mol%), n-hexane (0.05 M), rt, 24 h. cHPLC isolated yield. dDisulfide 5c was formed as the major side product.

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