Fig. 9: Schematic illustration of the mechanism of FOXQ1 transcriptional regulation.
From: FOXQ1 recruits the MLL complex to activate transcription of EMT and promote breast cancer metastasis
A proposed model illustrates that FOXQ1 directly recruits RbBP5 to the promoters of EMT target genes to facilitate MLL complex assembly, H3K4me3, and transcriptional activation.
