Table 4 Cox proportional hazards regression model for mortality

From: Immunomodulatory fecal metabolites are associated with mortality in COVID-19 patients with respiratory failure

Characteristic

HR

95% CI

p-value

Age

1.05

1.01, 1.08

0.010

Chronic kidney disease

1.09

0.42, 2.81

0.861

SOFA score

1.44

1.23, 1.68

3.59e-06

Vancomycin administration

0.41

0.17, 1.00

0.051

Admission location

   

Emergency department

–

–

 

Hospital medicine

1.49

0.59, 3.73

0.399

Outside hospital

0.18

0.04, 0.86

0.032

Microbiome metabolic profile

1.65

1.18, 2.31

0.003

  1. Variables with unadjusted p-values < 0.3 from the univariate analysis (Table 2) were included in the multivariate analysis. Unadjusted p-values were obtained from a likelihood ratio test and reported as exact values (n = 68 independent samples from patients).
  2. HR hazard ratio, CI confidence interval.
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