Fig. 4: Reduction of cross-neutralisation to the Omicron. | Nature Communications

Fig. 4: Reduction of cross-neutralisation to the Omicron.

From: Safety and immunogenicity following a homologous booster dose of CoronaVac in children and adolescents

Fig. 4

a Paired neutralising antibody titres against the prototype SARS-COV-2 (blue) and the Omicron (red) in Cohort 1, 1.5 μg group (n = 85). b Paired neutralising antibody titres against the prototype SARS-COV-2 (blue) and the Omicron (red) in Cohort 1, 3.0 μg group (n = 85). c Paired neutralising antibody titres against the prototype SARS-COV-2 (blue) and the Omicron (red) in Cohort 2, 1.5 μg group (n = 85). d Paired neutralising antibody titres against the prototype SARS-COV-2 (blue) and the Omicron (red) in Cohort 2, 3.0 μg group (n = 82). Dots are reciprocal neutralising antibody titres for individuals in the per-protocol population. Numbers above the dots are GMTs. Numbers above the short horizontal lines are reduction folders of cross-neutralisation comparisons between prototype and Omicron. The dotted horizontal line represents the seropositivity threshold (1:8). Titres lower than the limit of detection (1:4) are presented as half the limit of detection. GMT geometric mean titre.

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