Fig. 7: Human homolog miR-3074-3p regulating Cav-1 is identified as a potential signature in leukoaraiosis. | Nature Communications

Fig. 7: Human homolog miR-3074-3p regulating Cav-1 is identified as a potential signature in leukoaraiosis.

From: Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in mice

Fig. 7

a The univariate and multivariate logistic regression analysis with odds ratio (OR) values for leukoaraiosis. In the univariate analysis, the OR values, 95% confidence intervals (CIs), and their P-values represent the odds of leukoaraiosis of the covariates listed in the table. In the multivariate analysis, the OR values, 95% CIs and their P-values represent the odds of leukoaraiosis after adjusting for the covariates listed in the univariate analysis. The green dots indicate the OR value for the listed variable, and the lines indicate 95% CI. OR to the right of the grey midline (where OR = 1) indicate higher odds of leukoaraiosis while OR to the left of the midline indicate lower odds of leukoaraiosis. n = 66 in control and n = 88 in case. b Linear Regression assessing the association between hsa-miR-3074-3p and Cav-1 in patients with leukoaraiosis. The solid line represents the regression line and dashed lines represent the 95% CI. n = 66 in control and n = 88 in case. c, d Real-time PCR showing the serum hsa-miR-3074-3p and Cav-1 level in patients with mild or severe leukoaraiosis (n = 66 in control and n = 88 in case; mean ± SD.; unpaired t-test). Dots are all the data points including outliers. Source data are provided as a Source Data file.

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