Fig. 2: ACA community clusters are enriched for functional glycan classes and associated with type 1 diabetes phenotypes.
From: Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes
a Bubble chart showing glycan classes enriched (lighter blue and larger bubble size) in each ACA cluster calculated using fisher’s exact test. b Forest plot showing linear model for the first principal component of each glycan cluster against the clinical variables age at blood draw, presence of first degree relative with T1D, non-progression to T1D, progression to T1D, HLA risk, and sex in DAISY participants (n = 112). Effect size (dots) and 95% confidence interval (bars) are presented. All p values were two sided and a p < 0.05 was considered significant (significant associations are displayed as red, while non-significant associations are displayed as black). Source data are provided as a Source Data file.
