Fig. 3: The proportion of DC subpopulations and mononuclear macrophage subpopulations changed after CD39i treatment. | Nature Communications

Fig. 3: The proportion of DC subpopulations and mononuclear macrophage subpopulations changed after CD39i treatment.

From: Single cell sequencing reveals that CD39 inhibition mediates changes to the tumor microenvironment

Fig. 3

A, B The DCs were clustered into 6 clusters according to classical markers. C The expression of function-related genes in different DC subpopulations from the control group and the CD39i treatment group. D The proportion of DC subpopulations derived from the control group and CD39i treatment group (3 subcutaneous tumors from 3 mice mixed 1:1:1). EG There were no differences in mature, regulatory, and migration related functional gene expression after CD39i treatment. HJ. The mononuclear macrophages showed greater heterogeneity and a large number of different subpopulations, but the proportion of each subpopulation and the functional gene expression levels were not noteworthily changed after CD39i treatment.

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