Table 1 Characteristics of primary/recurrent patient cohort and tumors
Breast | Ovarian | Total | ||
---|---|---|---|---|
Patients | 13 | 14 | 27 | |
Tumors | Primary | 13 | 14 | 27 |
Recurrent | 18 | 22 | 40 | |
Total | 31 | 36 | 67 | |
Number of recurrences collected per patient | 1 | 9 | 11 | 20 |
>1 | 4 | 3 | 7 | |
Germline mutation | BRCA1 | 9 | 10 | 19 |
BRCA2 | 4 | 4 | 8 | |
Estrogen receptor (ER) status of primary tumor | ER+ | 4 | N/A | 4 |
ER- | 9 | N/A | 9 | |
Stage at diagnosis | I | 2 | 1 | 3 |
II | 8 | 3 | 11 | |
III | 2 | 8 | 10 | |
IV | 0 | 1 | 1 | |
Unreported | 1 | 1 | 2 | |
Treatment receiveda,b | Platinums | 3 | 14 | 17 |
PARPic | 1 | 4 | 5 | |
Chemotherapy | 13 | 14 | 27 | |
Hormonal therapy | 5 | 3 | 8 | |
Radiation | 7 | 3 | 10 |