Fig. 5: Distinct expression of lineage-defining transcription factors among clonally expanded T cells in CSF of ALS patients.
From: T cell responses at diagnosis of amyotrophic lateral sclerosis predict disease progression
t-SNE plots of 10X scRNA-seq data showing expression of GATA3, Eomesodermin, Tbet, and RORγt with the percentage of positive cells (shown in purple) noted (A). Quantification of GATA3, Eomesodermin, Tbet, and RORγt expressing cells among expanded (>5 identical TCR sequences) and non-expanded (≤5 identical TCR sequences) T cells. The p values were calculated using the chi-squared test (B).
