Fig. 3: Constructive or destructive interference of deformation patterns induced by prestin’s different orientations. | Nature Communications

Fig. 3: Constructive or destructive interference of deformation patterns induced by prestin’s different orientations.

From: Lipid-mediated prestin organization in outer hair cell membranes and its implications in sound amplification

Fig. 3

Heatmaps of phospholipid height in the outer (a) and inner (b) leaflets are calculated using the procedure described in Fig. 2. The prestin dimers are placed at (x, y) = (100, 100) Å and (300, 100) Å, respectively. The orientation of Dimer I (angle with respect to the x axis) is specified on the left, and for Dimer II on the top of each panel. Given the symmetry relation between prestin’s protomers, four angles (0°, 45°, 90°, and 135°) for each prestin dimer are sufficient to cover all possible orientations (at 45° intervals), resulting in 16 different combinations of two dimers. The protein cross-sectional area in each leaflet is drawn in red.

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