Fig. 1: Comparison of vascular and glomerular amyloid deposits and fibrils.
From: Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
a Light microscopy images of renal tissue sections from two patients with the vascular or glomerular variant of systemic AA amyloidosis each (patients I and II). Each section was stained with anti-AA antibody (brown). Dotted lines: glomeruli. Black arrows: arteriole walls. Scale bar: 100 µm. Each micrograph is representative for at least three micrographs recorded from the respective patient. b Coomassie blue-stained denaturing protein gels of the fibrils extracted from patient I and II. The bars and the asterisks indicate the fibril proteins. The experiment was performed independently at least three times with similar results. c Scanning electron microscopy images of AA amyloid fibrils from the patient I after platinum side shadowing. Yellow (left twist) arrowheads are drawn to guide the eye. Scale bar: 50 nm. The fibril images are representative for the fibrils on at least three micrographs obtained with this sample. Source data are provided as a Source Data file.
