Fig. 6: Single-cell TCR-sequencing of M198–206-specific CD8+ T cells. | Nature Communications

Fig. 6: Single-cell TCR-sequencing of M198–206-specific CD8+ T cells.

From: Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-19

Fig. 6

a UMAP shows clonal expansion of M198–206-specific CD8+ T cells. Each color indicate the number of cells observed for each clone. Yellow, three or more cells; red, two cells; blue, single-cell; green, others. The cells from time-course study samples (Hashtag 2, 3, 4, and 6, see Supplementary Table 3) were omitted from the analysis. b Each T cell clone having common TCRβ1, TCRβ2, and TCRβ4 were shown in UMAPs. Colors represent different clones as indicated. c Longitudinal analysis of T cell clones of a moderate COVID-19 convalescent, CV-001 from the list of Top20 clones were shown in different colors as indicated on UMAP.

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