Fig. 8: RasGRP1 expression correlates with the overall survival of cancer patients.

a–l The survival curves determined through Kaplan–Meier plot profiling (http://kmplot.com/analysis/) of cancer patients stratified according to high and low RasGRP1 expression. m Schematic representation showing RasGRP1 effects in promoting proinflammatory cytokine IL-6 production and decreasing the probability of inflammation-associated cancer in an mRNA-dependent or protein-dependent manner.