Fig. 4: The scope of internal alkenes. | Nature Communications

Fig. 4: The scope of internal alkenes.

From: Ligand-enabled Ni-catalyzed hydroarylation and hydroalkenylation of internal alkenes with organoborons

Fig. 4

The values under each structure indicate isolated yields. The regioselectivity was determined by analysis of the crude 1H NMR (rr > 99/1 for all substrates) and the dr was determined by GC. Reaction conditions: 4 (0.2 mmol, 1.0 equiv), 2a (0.6 mmol, 3.0 equiv), Ni(2-NH2-5-MeC6H3SO3)2 (10 mol%), L14 (10 mol%), Na3PO4 (0.6 mmol, 3.0 equiv), t-AmylOH (1.0 mL), 80 °C, N2, 24 h. The Z/E mixtures were used for most of substrates. For 5q and 5v, (E)-4q and (E)-4v were used; For 5s, (Z)-4s was used.

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