Fig. 3: Single platform features and the corresponding clinical prognosis. | Nature Communications

Fig. 3: Single platform features and the corresponding clinical prognosis.

From: Multi-omics analysis identifies osteosarcoma subtypes with distinct prognosis indicating stratified treatment

Fig. 3

A Transcriptional clustering based on the top 10% most variable genes (1820) across 101 samples. Each column represents one sample and rows indicate genes. B Kaplan–Meier curves for overall survival based on transcriptional clusters (log-rank test). C Copy number clustering based on SCNAs identified by GISTIC 2.0 in 116 samples. Each column represents one sample, and rows indicate CNA peaks. D Kaplan–Meier curves for overall survival based on CNA clusters (log-rank test). E DNA methylation clustering based on the top 8000 variably methylated CpG sites in 116 samples. Each column represents one sample and rows indicate CpG sites. F Kaplan–Meier curves for overall survival based on DNA methylation clusters (log-rank test). Asterisks define significance levels (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001).

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