Fig. 9: MSSR applications in fluorescence microscopy. | Nature Communications

Fig. 9: MSSR applications in fluorescence microscopy.

From: Extending resolution within a single imaging frame

Fig. 9

MSSR operates over images acquired with most fluorescence microscopy modalities available (e.g., widefield, confocal, light-sheet, etc.), denoted by the text in green. It can be applied to achieve enhanced image resolution, SNR and contrast in live-cell imaging, single-particle tracking, deep tissue and volumetric imaging, among others (denoted by the text in pale blue). Some examples of these applications are detailed in the main text and Supplementary Note 10. FF-SRM Fluorescence Fluctuation-based Super-Resolution Microscopy, SMLM Single-Molecule Localization Microscopy, STED Stimulated Emission Depletion microscopy, SIM Structured Illumination Microscopy, SPIM Selective Plane Illumination Microscopy, EPI Epifluorescence, HiLo Highly inclined and Laminated optical microscopy, TIRFM Total Internal Reflection Fluorescence Microscopy, CLSM Confocal Laser-Scanning Microscopy. Scale bars: a 500 nm; b 2 μm; c no scale provided; d 2 μm; e 20 μm, insets = 5 µm.

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