Fig. 8: Branched F-actin inhibits myosin motions through volume exclusion.
From: F-actin architecture determines constraints on myosin thick filament motion
Initial and final state of a network with Arp 2/3-nucleated F-actin (cyan) a and actomyosin overlay where motors are shown in red b CA = 200 μM. RM = 0.01. RArp2/3 = 0.01. LM = 1302 nm. Scale bar = 1 μm. c Ensemble average MSD of myosin with various Arp 2/3: actin ratio (RArp2/3) with (solid triangles, boxed legends) and without (hollow circles) volume exclusion (VE). d Ensemble average MSD of myosin with various myosin length (LM) with (solid squares, boxed legends) and without (hollow circles) VE. In c, and d, gray dashed lines indicate slope of 1.
