Fig. 9: Arp 2/3-nucleated F-actin confines myosin thick filaments.
From: F-actin architecture determines constraints on myosin thick filament motion
a Super-resolution z-stack image for Arp 2/3-nucleated F-actin (left), myosin thick filaments (middle), and merged image of F-actin (magenta) and myosin (cyan). Square image on the right is a zoomed in image of myosin thick filaments embedded in branched F-actin network. Scale bar is 5 μm. The actin (red) and myosin (black) normalized intensity plots as a function of depth z are on the left of actin z stack, respectively. Three independent experiments were done with similar results. b Diagram of myosin thick filaments within Arp 2/3-nucleated F-actin network.
