Fig. 5: DBS-induced expression of WSN markers. | Nature Communications

Fig. 5: DBS-induced expression of WSN markers.

From: Hypothermia evoked by stimulation of medial preoptic nucleus protects the brain in a mouse model of ischaemia

Fig. 5

a, c Immunohistochemical staining of c-Fos on coronal brain sections at the bregma point as indicated. b, d In situ RNAScope labelling of Adcyap1 and c-Fos mRNAs. e–g Higher magnification images of c-Fos staining (c), and the co-localisation of c-Fos with BDNF (f) and c-Fos with Adcyap1. h Quantifications of the ratio of c-Fos positive cells in the indicated area against the total numbers in the POA. i The ratio of co-localisation between c-Fos and BDNF in the MPN and MPA. j The ratio of co-localisation between c-Fos and Adcyap1 in the MPN and MPA. Scale bar = 100 µm. Data were mean ± s.e.m (n = 5 mice). Source data are provided as a Source Data file.

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