Fig. 4: Interaction of EV-Pd-Pt and Pd-Pt nanoparticles with S. aureus and E. coli, respectively.

a CLSM images of E. coli and S. aureus treated with Pd-Pt and EV-Pd-Pt (Pd-Pt concentration of 50 μg/mL) for 30 min, respectively. b CLSM tomography images of E. coli and S. aureus after 30 min incubation with Pd-Pt and EV-Pd-Pt nanoparticles, respectively. Red and green fluorescent signals represent Cy 5.5-labeled nanoparticles and SYTO 9-stained bacteria, respectively. Experiments were repeated three times independently with similar results.