Table 2 Seroprevalence and incidence of EV-A71 infections by serology in study participants of the Children cohort and that standardized using the age structure of the children in Anhua County (a cutoff titre of 16)
Age of study participants | Seroepidemiological outcomes of study participants | Seroepidemiological outcomes standardized using the age structure of the children in Anhua County | |
|---|---|---|---|
Seroprevalence | |||
Baseline visit, 2013 | Aged 1–9 years | 57% (55–59%) | 61% (58–65%) |
Follow−up visit 2, 2014 | Aged 2–10 years | 62% (60–64%) | 66% (62–70%) |
Follow−up visit 4, 2015 | Aged 3–11 years | 67% (65–69%) | 70% (66–74%) |
Follow−up visit 6, 2016 | Aged 4–12 years | 73% (71–75%) | 75% (71–79%) |
Incidence of EV-A71 infections | |||
2013/14 | Aged 1–9 years at baseline visit in 2013 and 2–10 years at the follow-up visit 2 in 2014 | 5.4% (4.5–6.5%) | 4.8% (4.0–5.9%) |
2014/15 | Aged 2–10 years at the follow-up visit 2 in 2014 and 3–11 years at the follow-up visit 4 in 2015 | 5.4% (4.5–6.5%) | 4.8% (3.9–6.0%) |
2015/16 | Aged 3–11 years at the follow-up visit 4 in 2015 and 4–12 years at the follow-up visit 6 in 2016 | 7.8% (6.7–9.2%) | 6.8% (5.7–8.3%) |
