Fig. 1: Creb5 and Gdf5 expression overlap in the developing synovial joint interzones.
From: Creb5 coordinates synovial joint formation with the genesis of articular cartilage

a, b Gene expression in E13.5 and E14.5 forelimbs from WT mice assayed by multiplexed RNAscope FISH. c Immunofluorescent staining of E14.5 and E18.5 forelimbs from WT mice for Creb5 and DAPI (to visualize nuclei). The articular perichondrium (yellow arrows) and metaphyseal/diaphyseal perichondrium (white arrows) are indicated. Shoulder (S) and Elbow (E) indicated. Similar results were obtained in at least two independent biological repeats. Scale bar equals 200 microns.