Table 1 Baseline characteristics of 62 MSI-H CRC patients receiving PD-1 blockade

From: Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer

 

With inflammatory conditions

Without inflammatory conditions

Total

14

48

Gender

Male

9 (64.3%)

33 (68.8%)

Female

5 (35.7%)

15 (31.2%)

Median age (range)

34 (20~73)

46 (19~67)

Family history

Yes

6 (42.9%)

28 (58.3%)

No

8 (57.1%)

20 (41.7%)

Histology

Adenocarcinoma

10 (71.4%)

40 (83.3%)

Mucinous Adenocarcinoma

4 (28.6%)

8 (16.7%)

Receiving PD-1 blockade combined with non-ICI drugs

Yes

9 (64.3%)

21 (43.8%)

No

5 (35.7%)

27 (56.2%)

  1. MSI-H High microsatellite instability, CRC Colorectal cancer, ICI Immune checkpoint inhibitor.