Table 2 Univariate and multivariate Cox proportional hazards regression for PFS

From: Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer

Variable

No. of cases

HR (95% CI)

P

Inflammatory conditions

No

48

1.000 (ref)

–

Yes

14

5.494 (1.652~18.273)

0.005

Histology

Adenocarcinoma

50

1.000 (ref)

–

Mucous adenocarcinoma

12

4.149 (1.256~13.701)

0.020

Family history

No

28

1.000 (ref)

–

Yes

34

0.286 (0.076~1.083)

0.065

Multivariable

Inflammatory conditions

No

 

1.000 (ref)

–

Yes

 

4.886 (1.445~16.520)

0.011

Histology

Adenocarcinoma

 

1.000 (ref)

–

Mucous adenocarcinoma

 

3.539 (1.051~11.918)

0.041

  1. The statistical tests were two-sided, and variable with P value <0.05 was included in multivariate Cox proportional hazards regression. No adjustments were made.
  2. PFS Progression-free survival, HR Hazard ratio, CI Confidence interval.
Back to article page