Fig. 5: Sub-clustering analysis of T cells identifies major T cell subclusters in skin tissues.
From: Single-cell sequencing shows cellular heterogeneity of cutaneous lesions in lupus erythematosus
a, f t-SNE plots distribution of T cell subclusters (SCs) in epidermis (a) and in dermis (f). b, g Bar plots show the proportions of cells from HC, DLE, and SLE in T cell SCs of epidermis (b) and dermis (g). d, i Heatmaps show the specific classic gene expression in SCs of epidermal (d) and dermal (i) T cells. The annotation of rows shows the classical subtypes of T cells with marker genes. CTL: Cytotoxic T Lymphocyte; ISG: interferon-stimulated gene. c, h Heatmaps indicating the top 10 differentially expressed genes between each SC of T cells in the epidermis (c) or dermis (h). e, j Bubble diagrams show the enriched Gene Ontology (GO) biological process (BP) terms in HC, DLE and SLE group of epidermis (e) and dermis (j). Source data are provided as a Source Data file.
