Fig. 1: Peptidoglycan biosynthesis and MraY inhibitors.
From: Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY
a A lipid cycle of peptidoglycan biosynthesis and b chemical structure of sphaerimicin A. IC50 50% inhibitory concentration, MIC minimum inhibitory concentration, PBP penicillin-binding protein.
