Fig. 4: Detection of loops at lower sequencing depths.
From: Reference panel guided topological structure annotation of Hi-C data
a Number of loops predicted by different tools at 5% FDR, for decreasing number of valid intra-chromosomal read pairs. b Venn diagram of loops predicted from Hi-C data of different sequencing depths by RefHiC. c–f Number of RefHiC loop predictions supported by experimental GM12878 ChIA-PET/HiCHIP data (test chromosomes chr15-17) at different levels of sequencing coverage: CTCF ChIA-PET (c), RAD21 ChIA-PET (d), SMC1 HiCHIP (e), H3K27ac HiCHIP (f).
