Fig. 1: Micropatterning of holey carbon EM grids using photomolecular adsorption.
From: Morphological control enables nanometer-scale dissection of cell-cell signaling complexes
a Schematic of patterned holey carbon film of gold mesh grid, with custom ECM patterns surrounded by a bio-passivation layer. b Grids are placed on a thin PDMS platform to eliminate physical contact with the carbon film, which is encompassed by a thicker PDMS ring to confine liquid on the grid. c Digital masks with custom patterns are projected through the carbon film to degrade the bio-passivation layer. d Adsorption of Oregon green gelatin to degraded regions of 50 × 50 µm squares within a 10 × 10 array. Scale bar is 30 µm.
