Table 1 Genes that do not return to baseline 2 months after recovery from COVID-19

From: Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence

Gene ID

Gene name

Estimate (recovery - pre-infection)

P-value

BH-adjusted P-value

ENSG00000236304

lncRNA

1.84

5.37E-08

9.20E-04

FSTL1

Follistatin Like 1

1.17

1.60E-07

1.37E-03

PTGS1

Prostaglandin-Endoperoxide Synthase 1

0.64

3.69E-07

2.11E-03

SPOCD1

SPOC Domain Containing 1

1.31

6.41E-07

2.53E-03

CXCL5

C-X-C Motif Chemokine Ligand 5

1.84

7.39E-07

2.53E-03

ALOX12

Arachidonate 12-Lipoxygenase, 12 S Type

1.33

1.24E-06

3.53E-03

PF4

Platelet Factor 4

1.53

1.71E-06

3.91E-03

ESAM

Endothelial Cell Adhesion Molecule

1.18

1.83E-06

3.91E-03

MT-RNR1

Mitochondrially Encoded 12 S RRNA

1.00

2.61E-06

4.13E-03

MMD

Monocyte To Macrophage Differentiation Associated

0.77

2.80E-06

4.13E-03

ENSG00000240093

lncRNA

-0.71

2.82E-06

4.13E-03

MTURN

Maturin, Neural Progenitor Differentiation Regulator Homolog

0.54

3.11E-06

4.13E-03

GNG11

G Protein Subunit Gamma 11

1.53

3.13E-06

4.13E-03

CAVIN2

Caveolae Associated Protein 2

1.15

4.51E-06

5.52E-03

DOK6

Docking Protein 6

1.59

5.00E-06

5.71E-03

LINC00989

lncRNA

1.25

5.76E-06

5.81E-03

SPARC

Secreted Protein Acidic And Cysteine Rich

1.65

6.07E-06

5.81E-03

PF4V1

Platelet Factor 4 Variant 1

1.60

6.11E-06

5.81E-03

ABLIM3

Actin Binding LIM Protein Family Member 3

1.41

6.88E-06

6.07E-03

MFAP3L

Microfibril Associated Protein 3 Like

0.74

7.09E-06

6.07E-03

CALD1

Caldesmon 1

1.78

7.79E-06

6.23E-03

ITGB5

Integrin Subunit Beta 5

1.10

8.00E-06

6.23E-03

LINC01750

lncRNA

2.00

1.13E-05

8.22E-03

PCSK6

Proprotein Convertase Subtilisin/Kexin Type 6

1.22

1.15E-05

8.22E-03

PVALB

Parvalbumin

2.04

1.46E-05

9.97E-03

  1. Genes that are significantly differentially expressed (1% FDR, LMM) in recovery versus pre-infection samples (n = 24 samples from 12 patients). Estimate represents the estimated difference in log CPM (counts per million). BH=Benjamini-Hochberg. A complete table including all genes tested can be found in Supplementary Data 1s.