Fig. 7: Bulk tissue cell deconvolution in ALS subtypes.
From: Molecular subtypes of ALS are associated with differences in patient prognosis
a Cell type percentages in the prefrontal and motor cortices for all patient samples considered in this study. b Fractions of cell types in the frontal and motor postmortem cortex, considered in the context of the ALS subtypes. Significant differences in cell type percentages were assessed using a two-sided Wilcoxon rank sum test with Bonferroni p-value adjustment. Adjusted p-values are denoted using the following scheme: *** p < 0.001; **p < 0.01; *p < 0.05. The median is indicated by the solid black line, and first and third quartiles are captured by the bounds of the box. Boxplot whiskers are defined as the first and third quartiles ± interquartile range times 1.5, respectively, and outliers are denoted as solid black points. Minimum and maximum values are captured by the lowermost and uppermost points, respectively, or whisker bound if no outliers are shown. Source data are provided as a Source Data file, including exact p-values for all comparisons.
