Fig. 3: Structure of the LiRecT monomer, comparison with RAD52, and interactions with DNA.
From: Structure of a RecT/Redβ family recombinase in complex with a duplex intermediate of DNA annealing
Monomers of LiRecT (a) and RAD52 (b) are shown in similar orientations with their common core folds in cyan and extraneous segments in green. The DNA backbones are drawn with the inner strand in yellow and the outer strand in orange (for LiRecT only). The DNA binding groove is formed by the 2 central α-helices (α2, α3), the β1–β2 hairpin, and αE-αD (LiRecT) or β3–β5 (RAD52). RAD52 is drawn with coordinates from PDB accession ID 5XRZ30. Close-up views of LiRecT interactions with the inner strand (c), outer strand (d), and β1-β2 hairpin (e). Hydrogen bonds within 3.5 Å and ion pairs within 6 Å are shown as dotted lines.
