Fig. 1: Sources of alternative N-termini. | Nature Communications

Fig. 1: Sources of alternative N-termini.

From: Thousands of human non-AUG extended proteoforms lack evidence of evolutionary selection among mammals

Fig. 1

a Transcript with both major annotated proteoform and N-terminally extended non-AUG (NUG) initiated proteoform. b Transcript with sole non-AUG-initiated (NUG) proteoform. c Transcript 1 has an extra CDS exon relative to transcript 2, while transcript 3 has a different transcription starts. As a result, non-coding parts of the first CDS exons in transcripts 2 and 3 exhibits protein-coding evolution. Green bars represent start codons, red bars show stop codons. Thick blue bars represent coding exons, thin blue bars are non-coding exons.

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