Fig. 6: Macroscopic, histopathological, and biochemical analysis of liver fibrosis.
From: Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
a Representative images of livers and liver sections stained with hematoxylin and eosin (H&E) or Picrosirius red (representative dataset from n = 5/group). Black arrows indicate apoptotic hepatocytes. b Morphometric quantification of Picrosirius red stained areas by ImageJ software (n = 5/group). c Quantification of serum alanine aminotransferase (ALT, n = 5/group). d Quantification of serum aspartate aminotransferase (AST, n = 5/group). e Quantification of serum total bilirubin (TBIL, n = 5/group). Data are presented as mean ± SD. ns not significant; *p < 0.05; ***p < 0.001. b–e one-way ANOVA with Tukey’s correction. Source data are provided as a Source Data file.
