Fig. 5: Assessment of binding across multiple variants simultaneously using SLISY. | Nature Communications

Fig. 5: Assessment of binding across multiple variants simultaneously using SLISY.

From: The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

Fig. 5

a Assessing clones across multiple RBD variants. UpSet plot includes upright bars that represent the total number of cross-reactive clones in each intersection. Filled circles below bars represent the variants that represent the intersecting set. Intersecting sets that have fewer than 6 cross-reactive clones were not represented. Horizontal bars represent the total number of clones that had a SLISY Ratio of ten and above for each of the proteins. Created with BioRender.com. b SBR for selected clones across variants. c ELISA for selected clones across variants. Error bars represent standard deviation of means (n = 3). Source data are provided as a Source Data file.

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