Fig. 3: Acute and reversible NASH-like pathology in adult SRSF1 HKO mice. | Nature Communications

Fig. 3: Acute and reversible NASH-like pathology in adult SRSF1 HKO mice.

From: Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death

Fig. 3

Representative images of H&E, Oil Red O (red, neutral lipids), and Sirius Red (red, collagen) histological staining of liver tissue harvested from wildtype (WT) and SRSF1 HKO mice at the indicated ages (n = 6 biologically independent animals per group). Yellow and black arrows in H&E staining indicate inflammatory infiltration and ballooning degeneration, respectively. Scale bar = 100 microns. Source data are provided as a Source Data file.

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